The Lord Jesus Christ Himself made the most direct and unambiguous statement on eternal security in all of Scripture. He declared that He gives unto His sheep eternal life — not temporary life, not probationary life, not conditional life — eternal life. And He added the absolute guarantee: they shall never perish. The word "never" in the Greek is an emphatic double negative, the strongest negation possible in the language. It means "absolutely not ever, under any circumstances."
But Christ did not stop there. He continued by stating that no one is able to pluck them out of His hand. And lest anyone imagine that some force might overpower the Son, He declared that the Father, who is greater than all, holds them as well — and no one is able to pluck them out of the Father's hand. The believer is held in a double grip: the hand of the Son and the hand of the Father.
If a believer could lose their salvation, then Christ's promise is broken, His word is unreliable, and the term "eternal life" is a misnomer. But God cannot lie, and Christ's promises are sure. What He has given, He will not take back. What He holds, none can remove.